I first met Stuart in the early 1990s when he was beginning his PhD research.  I was part of the Manchester clinical team specialising in early onset dementias.  We had identified and characterised frontotemporal dementia (FTD) patients and were aware of the high familial incidence.  Stuart’s work on the genetics of FTD was therefore crucial and timely. Stuart was full of passion for his subject.  I recall having lunch with him one day while attending the 2002 International conference on Alzheimer’s disease in Stockholm.  We were in a lovely little restaurant in the old part of town.  I am not sure that Stuart noticed the beautiful surroundings. He talked non-stop and animatedly about his research and his ideas for our future collaborative work. His positivity and enthusiasm were infectious. That is how I shall remember him.