I was deeply saddened to hear of Claire’s passing. I had the privilege of working with Claire on the early development of our AAV platform, including efforts to increase vector yields, develop capsid libraries for tissue-targeted gene delivery, and advance several R&I and CVRM pipeline projects. I still remember how remarkably well Claire’s prostate cancer-targeted AAV performed in vivo. Claire was an outstanding scientist and leader—rigorous, creative, and exceptionally organized. Claire had a rare ability to move complex projects forward, bring people together, and ensure that no detail was overlooked. Working with Claire made the entire team better, and I greatly valued our time together. I am grateful for all I learned from Claire and for the lasting contributions Claire made to our work. My thoughts are with Claire’s family, friends, and all who knew Claire.